Cthrc1 gene

WebCTHRC1 is known to regulate extracellular collagen deposition and partake in vascular remodeling of arterial injury as a function of cellular response through the TGF-β and Wnt pathways. Moreover, mutation of the gene has been associated with carcinogenesis in a variety of cell and tissues, most notably esophageal adenocarcinoma and Barrett ... WebSep 23, 2024 · Through bioinformatics analyses and experiments, we confirmed that CTHRC1 is highly expressed in tissues and hepatoma cell lines. High expression of the CTHRC1 gene is associated with poor prognosis. Collectively, the results of the present study indicated that CTHRC1 may serve as a prognostic biomarker for HCC.

Identification and Verification of Potential Biomarkers in Gastric ...

WebJul 19, 2024 · Collagen triple helix repeat containing-1 (CTHRC1), highly expressed in multiple human solid tumors, has been identified as a tumor associated protein. … WebFeb 22, 2007 · We identified collagen triple helix repeat containing-1 (Cthrc1) as a novel gene expressed in the adventitia and neointima on arterial injury and found that it functionally increases cell migration while reducing collagen deposition. To address the in vivo role of Cthrc1, we generated transgenic mouse lines that constitutively overexpress … orbbec d-light https://marketingsuccessaz.com

Single-Cell RNA Sequencing Analysis Reveals a Crucial …

WebTreatment of cholestatic fibrosis by altering gene expression of Cthrc1: Implications for autoimmune and non-autoimmune liver disease Author links open overlay panel Zhaolian Bian a 1 , Qi Miao a 1 , Wei Zhong a 1 , Haiyan Zhang a , Qixia Wang a , Yanshen Peng a , Xiaoyu Chen a , Canjie Guo a , Li Shen a , Fan Yang a , Jie Xu a , Dekai Qiu a ... WebGenomic Mutations. 2 involving Cthrc1. Incidental Mutations. Mutagenetix , APF. Find Mice (IMSR) 20 strains or lines available. Comparison Matrix. Gene Expression + Phenotype. … WebApr 17, 2024 · Collagen triple helix repeat containing-1 (CTHRC1) has been identified as cancer-related protein. ... The Structural Features of CTHRC1. The CTHRC1 gene is located at chromosome 8q22.3, and it contains … orbbec astra cameras unity

CTHRC1 expression is a novel shared diagnostic and prognostic biomarker ...

Category:Pan-cancer analysis combined with experiments predicts CTHRC1 …

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Cthrc1 gene

Treatment of cholestatic fibrosis by altering gene expression of Cthrc1 …

WebMar 21, 2024 · CTHRC1 (Collagen Triple Helix Repeat Containing 1) is a Protein Coding gene. Diseases associated with CTHRC1 include Barrett Esophagus and Adenocarcinoma . Among its related pathways are Wnt … WebAug 7, 2024 · We reveal gene expression signatures that demarcate fibroblasts from mural cells and provide molecular signatures for cell subtype identification. ... C1qtnf3, and Cthrc1) their distribution in ...

Cthrc1 gene

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Web屈振杰 ，崔 琴. 内蒙古包钢医院1.肿瘤内科；2.消化内科，内蒙古 包头 014010. 胃癌是消化道常见的恶性肿瘤，其发病率及死亡率居恶性肿瘤第2位[1]。 WebFeb 8, 2024 · We assessed the cause of elevated CTHRC1 levels. DNA methylation, gene mutation, CNV was critically involved in genetic and epigenetic regulation and were …

WebJun 15, 2024 · Gene expression of Cthrc1 was significantly increased from day 3, peaked at day 5, and fell back at day10 after injury (Fig. 1a). To verify this result, we examined the … WebWe recently identified collagen triple helix repeat containing-1 (Cthrc1) as a novel gene induced in adventitial fibroblasts after arterial injury. Cthrc1 is a 30 kDa secreted protein that has the ability to inhibit collagen matrix synthesis. Cthrc1 is also glycosylated and retains a signal sequence consistent with the presence of Cthrc1 in the ...

WebApr 21, 2024 · One subpopulation, characterized by expression of Cthrc1 (collagen triple helix repeat containing 1), emerges in fibrotic lungs and expresses the highest levels of collagens. ... Gene expression ... WebSep 25, 2024 · Collagen triple helix repeat containing 1, a novel secreted protein in injured and diseased arteries, inhibits collagen expression and promotes cell migration. Circ …

WebOct 6, 2024 · According to the previous reports, the collagen triple helix repeat containing 1 (CTHRC1) causes tumorigenesis by modulating the tumor microenvironment, however, the evidence is limited to a few human cancer subtypes. ... (GEO) based datasets. During the analysis, we simply queue the CTHRC1 gene in these databases to acquire the KM …

WebJan 29, 2013 · Colorectal cancer (CRC) patients with peritoneal carcinomatosis (PC) have a poor prognosis. Over the last decade, increasing evidence has suggested that the Collagen Triple Helix Repeat Containing 1 (CTHRC1) gene is involved in cancer progression and invasion. In this study, we investigated the expression of CTHRC1 in CRC and its … orbbec astra githubWebOct 26, 2024 · The function of collagen triple helix repeat containing 1 (CTHRC1) as an oncogene has been reported in a growing number of publications. Bioinformatics … ipmitool event 3WebSep 9, 2008 · Methodology/Principal Findings. We identified collagen triple helix repeat containing-1 (Cthrc1) as a downstream target of bone morphogenetic protein-2 (BMP2) in osteochondroprogenitor-like cells by PCR-based suppression subtractive hybridization followed by differential hybridization, and found that Cthrc1 was expressed in bone … orbbec astra stereoWebMay 13, 2024 · A Relative mRNA level of CTHRC1 in primary CRC with metastasis (Mets) and primary CRC without (w/o) Mets using three … orbbec opencvWebDec 22, 2024 · The X-axis represent ligand and receptor pairs, with the first gene expressed on F13-Act-CTHRC1 cells and second gene expressed on the interacting cell types denoted in the Y-axis. Red: upregulated gene in tumor bulk RNA-seq. Blue: downregulated in tumor bulk (none present). ipmitool event logWebMar 21, 2024 · CTHRC1 serves as a pro-metastatic gene that contributes to NSCLC invasion and metastasis, which are mediated by upregulated MMP7 and MMP9 … orbbec astra opencvWebGene view. The gene view histogram is a graphical view of mutations across CTHRC1. These mutations are displayed at the amino acid level across the full length of the gene … orbbec inc