Clotrimazole hplc method

Author: hnpo

August undefined, 2024

WebSep 6, 2016 · A simple, reliable HPLC method was developed and validated for quantitation of clotrimazole in human plasma. Preparation was carried out using protein precipitation … Clotrimazole was obtained from Glenmark Laboratories Ltd, Mumbai, India. HPLC-grade acetonitrile LiChrosolv, water LiChrosolv, and methanol were procured from Merk Pvt. Ltd., Mumbai. Gelatin and sodium lauryl sulfate were procured from S D Fine-Chem Ltd, Mumbai. Gelatin films (3% w/w of clotrimazole) … See more The Younglin Acme 9000 HPLC system consisting of the components, 4 Channel Vacuum Degasser and Mixer SDV50A, Gradient Pump … See more Film equivalent to 10 mg of clotrimazole (332 mg) was taken in a 50 ml volumetric flask and dissolved in 40 ml of 1% sodium lauryl sulfate (SLS) … See more Ten milligrams of clotrimazole was weighed and transferred into 10 ml volumetric flask. 5 ml of the methanol was added to clotrimazole and sonicated for 10 min; the volume was made up to the mark with methanol (flask … See more A solution of clotrimazole in the mobile phase (10 μg/ml) was scanned in the range of 200–400 nm in a UV-VIS spectrophotometer, and λmaxwas selected from the UV … See more

A sensitive LC-ESI-MS/MS method for the determination …

WebOct 1, 2013 · Objective: A simple, sensitive, precise and accurate stability-indicating HPLC method has been developed and validated for … WebThe invention discloses clotrimazole cream and a preparation method thereof. The clotrimazole cream comprises components in percentage by mass as follows: 1% of clotrimazole, 17%-34% of oleaginous bases, 4%-6% of an emulsifying agent, 5%-10% of a moisturizer, 1.1%-3% of a preservative, 0.03%-0.05% of a complexing agent and the … corner sewing table with storage

(PDF) Development and Validation of New Analytical …

WebJan 22, 2024 · A simple stability-indicating high performance liquid chromatographic (HPLC) method has been developed which separates clotrimazole from impurities and decomposition products in bulk drugs, creams, tablets, and solutions. Average recovery data for drug substance added to placebos were: tablet, 99.8%; solution, 99.5%; and cream, … Webdetermined in different pharmaceutical preparations by HPLC [1,6-7]. Clotrimazole has been determined in different pharmaceutical preparations by: Titration method [2], gas … WebThe proposed HPLC method provide simple, accurate and reproducible quantitative analysis for determination of PNZ and LID and in tablet. The method was validated as per ICH guidelines. ... Development and Validation of Advance Simultaneous Equation Methods for Lidocaine Hydrochloride and Clotrimazole in Ear DropAsian J Pharm Res201552108 … corners failed to convert

Development and validation of HPTLC method for the …

Clotrimazole hplc method

Simultaneous HPLC Analysis of Betamethasone and Clotrimazole …

Webapplication of clotrimazole via a novel controlled release device provides potent retinal protection：通过一种新型的控释装置提供了有效的保护视网膜克霉唑的应用 WebTwo stability-indicating chromatographic methods for the determination of clotrimazole and its two acid induced degradation products, with dexamethasone acetate without prior separation. First method depends on RP-HPLC utilizing ODS-3 Inertsil C18 column. Mobile phase consists of acetonitrile:phosphate buffer (pH 6.0) in ratio (65:35, v/v) with flow rate …

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WebSep 30, 2007 · A novel simple and quick isocratic HPLC method for determination of clotrimazole and its two degradation products on a 3.5 μm Zorbax ® SB-Phenyl column … WebOct 1, 1992 · The present study, concerned with the development of HPLC methods suitable for the reliable analysis of imidazole antimycotic dosage forms (primarily creams), had the following objectives: (a) the provision of a selective chromatographic separation of all the cited antimycotic drugs; (b) the enhancement of the method sensitivity by means …

WebJun 25, 2024 · Although many researchers have investigated clotrimazole and itraconazole singly or in combination with other compounds, to the best of our knowledge, no HPLC method has been developed for the simultaneous determination of both drugs simultaneously, especially in microemulsion systems [16,17]. Finally, we performed an … WebApr 8, 2024 · A new simple, precise, accurate, economic and selective HPLC method has been developed and validated for the estimation of Beclomethasone …

Webnone of the reported methods describes a simple HPLC method for estimation of clotrimazole in gelatin film for-mulation. Furthermore, buffers were used in the mobile phase of reported HPLC methods. Thus, there was a need for a validated simple HPLC method to determine clotrimazole in gelatin film formulation without any pre-treatment …

WebAug 5, 2024 · It can be used in the form of pills, creams, and injections. It can also be used as immune suppression and as an anti-inflammatory. The chemical formula of …

WebDec 1, 2024 · Background Clotrimazole is used to treat topical vaginal yeast infections. Vaginal gelatin film formulations of clotrimazole were prepared, and the present study aims to develop an HPLC method for ... fanny cheyrou biographieWebMethods: The study design involved the establishment of an appropriate application time, which was determined by conducting a dose duration study. Subsequently, two bioequivalence studies were conducted: i) using the brand (Canesten Topical - 1% clotrimazole cream) as both the test and the reference product and ii) comparing … fanny chmelar翻译WebSep 30, 2007 · A novel simple and quick isocratic HPLC method for determination of clotrimazole and its two degradation products on a 3.5 μm Zorbax ® SB-Phenyl column (75 mm × 4.6 mm i.d.) using ibuprofen as an internal standard was described. The time of analysis was less than 6 min. The method has been completely validated, the results … corners farmWebJul 11, 2024 · National Center for Biotechnology Information fanny chevalier actriceWebMay 24, 2024 · Spectrophotometric and HPLC methods (10, 11) have been also described for analysis of BTD and CLO in binary mixture. Ternary mixture containing BTD, CLO … fanny chicken cape canaveralWebThe proposed HPLC-method can be successfully applied as a stabilit … High-performance liquid chromatographic technique has been developed for the determination or some azolcsantifungals namely, clotrimazole (CZ), ketoconazole (KZ) and fluconazole (FZ), in pure forms and in pharmaceutical formulations. The proposed HPLC-method can be ... fanny chobertWebFeb 19, 2024 · Clotrimazole can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and … fanny chiron